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differential lupus sle activation ana antinuclear arthritis autoantibodies autoimmune behcet classification cryofibrinogenemia gca giantcell macrophage mas mimickers myelitis myopathy myositis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Lymphoproliferative Disorders, Infection ... Drug-Induced, Inflammatory ... ANA #patterns #rheumatology ... #diagnosis #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... (rare), Arthritis ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... : - Arthritis ... - Hemolytic anemia ... #signs #symptoms ... #differential #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: - Ocular inflammatory ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
- Signs and Symptoms ... Episcleritis, Scleritis ... Hematological: Anemia ... #RA #Signs #Symptoms ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, particularly scleritis ... purpura: Strong sign ... ischemia • Skin: Erythematous ... : Ocular inflammatory ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... SLE], AOSD) • Infection ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (25-75%): Inflammatory ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... signs/sx of inflammation ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
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