8 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Sjögren Syndrome ... Lymphoproliferative Disorders, Infection ... Drug-Induced, Inflammatory ... #rheumatology #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... (rare), Arthritis ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... : - Arthritis ... - Hemolytic anemia ... #signs #symptoms ... #differential #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and Superficial temporal ... Symptoms (Sx) in ... purpura: strong sign ... : antibodies directed ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, particularly scleritis ... purpura: Strong sign ... and Superficial temporal ... : Ocular inflammatory ... #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... signs/sx of inflammation ... them, but urgent rheumatology ... #Signs #Symptoms ... #Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Framework Inflammatory ... papules and Gottron sign ... ) • Shawl sign ... slow onset and pattern ... Myositis #Myopathy #rheumatology