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differential sle neurology agglutinin ana antinuclear autoantibodies behcet classification cryofibrinogenemia hemolytic mimickers ms multiple myelitis myopathy myositis patterns tafro thrombocytopenia
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... #Lupus #Erythematosus ... #signs #symptoms ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... ) Blood (75%): Anemia ... #erythematosus # ... signs #symptoms ... #diagnosis #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Agglutinin Syndrome ... anemia • Cold ... Mycoplasma, EBV, HIV ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... photosensitivity, inflammatory ... rheumatologic diseases ... lupus erythematosus ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
as systemic lupus ... Symptoms (Sx) in ... purpura: strong sign ... Cryoglobulins • HIV ... #rheumatology #
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, particularly scleritis ... purpura: Strong sign ... ischemia • Skin: Erythematous ... : Ocular inflammatory ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
, vasculitis, sepsis ... Malignancy • Infections ... processes: • Systemic ... #rheumatology # ... hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (25-75%): Inflammatory ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
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