14 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... Risks factor for HIV ... peripheral blood smear, HIV ... #Diagnosis #Causes ... #Workup #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... • Rheumatoid Arthritis ... • CMV • HIV ... Lymphoblastic Leukemia (Pancytopenia ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
HCV, HBV Not ... fever • Drug reactions ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... Anemia #oncology #hematology ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
severe thrombocytopenia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
severe thrombocytopenia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
deficiency) • HIT ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Better call hematology ... about secondary causes ... you’ll do a good workup ... #workup #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
specifically immune thrombocytopenia ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... infections (acute HIV ... , HBV, EBV, VZV, ... gastric tumors • Hematology ... #diagnosis #hematology