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oncology causes adultonset aplastic chronic classification diffuse disease fatigue gap gca giantcell globulin hodgkins lad lymphadenopathy lymphoma protein proteingap signs
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... borrelia, Rubeola, HBV ... , HIV, HTLVI, Hantavirus ... #management #treatment ... #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... • Rheumatoid Arthritis ... • CMV • HIV ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... • Anemia • ... Malignancy Infectious ... • HIV Autoimmune ... #Diagnosis #Algorithm
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... #oncology #hematology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
infections (acute HIV ... , HBV, EBV, VZV, ... (RA, Temporal arteritis ... gastric tumors • Hematology ... #diagnosis #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... vs infection vs malignancy ... systemic complaints- anemia ... them, but urgent rheumatology ... #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
• Autoimmune hepatitis ... phenomenon (16%) MSK ... Malignancy Risk ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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