11 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
causes spinal cord ... While the pathophysiology ... an involuntary reflex ... Video by Dr. ... #Video #PhysicalExam
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Mixed upper and lower ... bladder and rectal reflex ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential ... and signs below ... , HIV, CMV, HTLV ... dysfunction • Abnormal reflexes ... disorders #diagnosis #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... history of cancer, HIV ... ) • Systemic symptoms ... infection (e.g., meningitis ... Diagnosis #Algorithm #neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... (IRIS): • In HIV ... Tuberculosis #diagnosis #differential ... #TB #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Diagnosis: • Spinal cord ... infarct • HIV ... diagnosis #causes #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... syphilis, and HIV ... motor neuron symptoms ... syndromes #lesions #differential ... #diagnosis #neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Herpesviruses (MCC: HSV ... Coltivirus Symptoms ... Acute meningeal signs ... culture or by serology ... #diagnosis #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... simplex virus, HIV ... diagnosis #management #neurology ... #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... multiple spinal cord ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology