293 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hemophagocytic Lymphohistiocytosis ... (HLH) Clinical ... lab findings in HLH ... consistent with HLH ... Hemophagocytic #Lymphohistiocytosis
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Algorithm for MAS / HLH ... #MAS #HLH #Hemophagocytic ... #Lymphohistiocytosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... (HLH) Definition ... / Diagnosis: HLH ... If no response HLH ... Hemophagocytic #Lymphohistiocytosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... (HLH) Pathophysiology ... • Familial HLH ... XLP) Acquired HLH ... Hemophagocytic #Lymphohistiocytosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
haemophagocytic lymphohistiocytosis ... (sHLH) What? ... hemophagocytic lymphohistiocytosis ... (HLH) that develops ... hypersensitivity syndromes • HLH
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... (HLH) Treatment ... Primary HLH: - ... HLH-94 Protocol ... Hemophagocytic #Lymphohistiocytosis
Diagnosis of Primary Amenorrhea
A diagnostic approach to primary amenorrhea. (FSH = follicle-stimulating hormone; LH = luteinizing
follicle-stimulating hormone; LH ... #Diagnosis #PrimaryCare
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
HLH 2.
A diagnostic approach to secondary amenorrhea. (DHEA-S = dehydroepiandrosterone sulfate; FSH = follicle-stimulating hormone; LH =
follicle-stimulating hormone; LH ... #Diagnosis #PrimaryCare
Causes of Female and Male Infertility - Differential Diagnosis Algorithm
Causes of Female Infertility:
 • Uterus -
hypogonadism) Low FSH/LH ... problem) High FSH/LH ... Algorithm #Causes #PrimaryCare