22 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... #Differential #Causes ... #Anesthesiology ... #Anesthesia #Checklist ... #Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
in Anaesthesia Causes ... decreased ETCO2 Symptoms ... Embolism #VTE #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... and positioning (e.g ... #Differential #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
Guidelines for Crises ... is conscious, symptoms ... Ischemia #Ischaemia #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
reservoir bag and APL ... blood gas, 12-lead ECG ... #Differential #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #management #treatment
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
reservoir bag and APL ... • Check ECG rhythm ... CardiacArrest #Checklist ... #Differential #Anesthesiology ... #Diagnosis #Management