16 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... . autoimmune, TB ... Myelodysplastic syndrome ... #Causes #hematology ... #secondary
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
in the US: Autoimmune ... ketoconazole, etomidate) Symptoms ... Causes of Secondary ... #Diagnosis #Management ... #Endocrinology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential Diagnosis ... Constitutional disorders, eg ... Chediak-Higashi syndrome ... drug reactions - Secondary ... #causes #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #management #treatment
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Type III Often Secondary ... Labs/Diagnosis: ... classification #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... with autoimmune ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology #
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Sclerosis (MS) is an autoimmune-mediated ... • Or brainstem syndromes ... Multiple Sclerosis Diagnosis ... progressive decline → Secondary ... #management #neurology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... Hypercortisolism - Diagnosis ... • Acne • If secondary ... #signs #symptoms ... #endocrinology