36 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... for specific symptoms ... glucocorticoid treatment ... (eg, skin or esophageal ... #Differential #diagnosis
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... #Differential #Causes ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management ... #Workup
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
thoracotomy is a better treatment ... Plan definitive management ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... and positioning (e.g ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #management #treatment
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
in Anaesthesia Causes ... decreased ETCO2 Symptoms ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... • Treatment: ... comparison #table #rheumatology ... #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... #diagnosis #hematology