11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease - Capillary ... Relapsing-remitting course +++ Clinical ... ) • IVIg 2 g/kg ... #diagnosis #management ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... nervous system (CNS ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... #Rheumatology # ... diagnosis #management ... #Dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... Treat primary cause ... #treatment #management ... #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Muscle atrophy may cause ... positive patients Treatment ... #rheumatology # ... dermatology