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rheumatology differential activation algorithm clinical cns common cvid erythematosus gangrenosum gca giantcell hypogammaglobulinemia immunodeficiency immunology lupus macrophage mas naildisorders neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
complaints- anemia ... identifies 85 to 95% of cases ... of the steroid treatment ... Treatment of GCA ... #Management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Constitutional disorders, eg ... Megaloblastic anemia-rare ... #causes #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... Rule out other causes ... and lower jaw Treatment ... diagnosis #management ... #Dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Nephrogenic DI Hematologic ... Arthralgia and Arthritis ... Adenocarcinoma Treatment ... Diagnosis #Management
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Diagnosis? ... Management of PG ... cyclosporine is used PG secondary ... treatment options ... clinical #photo #dermatology
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