10 results
Signaling Mechanism of PD-1 and PD-L1 and Inhibition of PD-1 Signaling in Microsatellite-Instability–High Cancers. MHC1 denotes
histocompatibility complex 1 #Pathophysiology ... #Honc #Pharm #PD1 ... MicrosatelliteInstability #NEJM
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
#Pathophysiology ... #GI #IM #NASH # ... NonAlcoholicFattyLiverDisease #NEJM
Hemorrhagic Shock Coagulopathy #Pathophysiology #Honc #Coagulopathy #HemorrhagicShock #NEJM
Coagulopathy #Pathophysiology ... #Honc #Coagulopathy ... HemorrhagicShock #NEJM
Radiation Injury
Acute Radiation Toxicity primarily affects rapidly dividing cells based on dosage
Hematopoiteic - Pancytopenia, Infection
 •
Onset <2 days GI ... , Dehydration, GI ... Hours Cardio/CNS ... Circuatory collapse, CNS ... admit to heme/onc
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
#Pathophysiology ... #Honc #IM #Spherocytosis ... HereditarySpherocytosis #NEJM
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
- anemia - CNS ... Delirium - GI ... Syndrome #diagnosis #pathophysiology
Upper endoscopy revealed a pigmented mass in the duodenal bulb (Panel A) and two additional masses
B) #Clinical #GI ... #Derm #Honc #Melanoma ... EGD #Metastatic #NEJM
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
#Pathophysiology ... #IM #Honc #Pharm ... Immunosuppression #NEJM
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
replicates within CNS ... induces vascular & CNS ... replication within GI ... and URT causes CNS ... peds #pediatrics #pathophysiology
Gastric Cancer in Chest Radiograph - A plain radiograph of the chest showed a round, irregular
Clinical #Radiology #GI ... #Honc #CXR #EGD ... GastricCancer #NEJM