25 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... NAFLD, Others • Mild ... LFTs #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Calculating a Reticulocyte Index (RI)
Reticulocyte Index = Absolute Reticulocyte Count / Maturation Correction
Absolute Reticulocyte Count =
reticulocytes x Patient's Hct ... / Normal Hct ... Index #RI #RPI #hematology ... #diagnosis #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Liver Function ... Liver Function ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
• Histology: Normal-mild ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... NAFLD • Others Mild ... Others #LFTs #Hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Chronic Disease Normal ... Renal Disease, Liver ... Reticulocytosis • Liver ... Algorithm #Causes #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... - If both are normal ... • Near normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... - If both are normal ... function may be abnormal ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... some patients) Normal ... : Alcohol use, Liver ... morphologic #mcv #differential ... diagnosis #causes #hematology