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diagnosis management algorithm hemophagocytic hlh lymphohistiocytosis arterial fatty hemeonc hyponatremia lfts liver liverenzymes nephrology obgyn obstetrics oncology pregnancy rheumatology summary
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Pregnancy - AFLP ... NAFLD • Others Mild ... • Pancreatic cancer ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Liver #Pregnancy #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Ischemic Liver, IBD ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... cytokines (TNFa,lL1, IL6 ... B-LNH), solid cancers ... PTLD), allogeneic HSCT ... treatment #summary #rheumatology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm in Cancer ... - and IL-2- induced ... VOD following HSCT ... chemotherapy, nausea
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... it is often a cancer ... Pathophysiology ... transplantation (HSCT ... Diagnosis #Management #Hematology
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