14 results
diagnosis management algorithm pathophysiology anemia blood oncology polycythemia product pulmonary reactions aflp amiodarone aplastic arterial autoimmune boop bruising cancer cryptogenic
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... #hepatology #obstetrics
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
BOOP • Type of interstitial ... Unknown • 6-7 cases ... - Imaging: • CXR ... , cavities • HRCT ... BOOP #pulmonary #ILD
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Hb > 16.5 g/dL/HCT ... : Hb > 16 g/dL/HCT ... Polycythemia - Acquired Causes ... disease, Smoking/CO ... Diagnosis #Algorithm #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Hb>16.5 g/dL, Hct ... Hb>16.0 g/dL, Hct ... : neuro, heme (bleeding ... Better call hematology ... Algorithm #workup #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Syndrome, Ischemic Liver ... , IBD • COVID- ... pathophysiology #hematology ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Acquired: • Mild ... discern these causes ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... Marrow hypoplasia/fatty ... • Allogeneic HSCT ... Anemia #oncology #hematology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
life: 45 days in fatty ... Exclude other causes ... Exclusion of other ILDs ... confirmatory findings on HRCT ... LDH • ↑ ESR, CRP
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
Why does the Hgb/Hct ... -6% drop in Hg/Hct ... 30 min and Hg/Hct ... concentrating Hg/Hct ... Decrease of Hg/Hct
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
May have drop in Hct ... Causes purpura & ... eruptions, diarrhea, liver ... coagulopathy & ↑bleeding ... diagnosis #management #hematology
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