18 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... EBV, CMV), Alcohol-related ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... , D, EBV, CMV, HSV ... • Toxic: Alcohol ... Causes #Acute #algorithm ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... HAV immunity; Liver ... #Management #Treatment ... #Hepatology
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... D/E, EBV, CMV, HSV ... Drugs (MDMA), Alcohol ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... infection with severe liver ... injury (INR > 2 ... mg/dL) or acute liver ... #management #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Failure Infections Alcohol-Associated ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis serologies, HCV ... hepatitis serologies, HCV ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... #differential #Hepatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology