46 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Cirrhosis • Chronic ... Viral Hepatitis ... • Acute Viral Hepatitis ... (>1000): • DILI
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... disease, Hepatic ... hepatitis fibrosis ... • Autoimmune hepatitis ... #hepatology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
antivirals (DAAs) for chronic ... hepatitis C virus ... DAAs #Antivirals #table ... #HepC #HepatitisC ... #Management #Pharmacology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Trauma: Shock liver ... Metabolic: Wilson Disease ... • Autoimmune hepatitis ... • Iatrogenic: DILI ... Transaminases #hepatitis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... serologic evidence of hepatitis ... HAV immunity; Liver ... Chronic Hepatitis ... #HepatitisB #HBV
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
disease, liver ... Alcohol-Associated Hepatitis ... Injury (DILI) ... Viral Hepatitis ... #diagnosis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
- Acute Viral Hepatitis ... , Toxic Hepatitis ... 5-10x normal - Chronic ... #LFTs #transaminitis ... #differential #diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... - ongoing ↑ LFTs ... disease 6-9 mo ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Autoimmune: Autoimmune hepatitis ... • NASH, Chronic ... viral hepatitis: ... #injury #hepatitis
Hepatitis B Phases and Treatment
Phase 1 - HBeAg+ Chronic Infection
Phase 2 - HBeAg+ Chronic Hepatitis
Phase 3
Hepatitis B Phases ... Hepatitis Phase ... Hepatitis Phase ... Burak @kwburak #HepatitisB ... #diagnosis #hepatology