10 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
quick guide on the common ... antivirals (DAAs) for chronic ... DAAs #Antivirals #table ... infectiousdisease #hepatology ... #Management #Pharmacology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... 5-10x normal - Chronic ... normal - Hemolysis, NASH ... #Injury #hepatology ... #LFTs #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic - less common ... presentation • Chronic ... - ongoing ↑ LFTs ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... disease: > 2 • NASH ... , Chronic viral ... : > 3 • Chronic ... #injury #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 • NASH ... , Chronic viral ... : > 3 • Chronic ... transaminitis #LFTs
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2 ... #HepBV #HBV #Treatment ... #Indications #management ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... - Symptoms of chronic ... arthralgias) are common ... injury, though ... #Hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... disease • Liver ... diseases and hepatitis ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Related Acute Lung Injury ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Related Acute Lung Injury ... eruptions, diarrhea, liver ... Transfusions #diagnosis #management ... #hematology #reactions