18 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
quick guide on the common ... antivirals (DAAs) for chronic ... DAAs #Antivirals #table ... infectiousdisease #hepatology ... #Management #Pharmacology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... between the above phases ... HAV immunity; Liver ... Chronic Hepatitis ... #HepatitisB #HBV
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common ... hepatitis Anti-CCP ... Dermatomyositis Anti-LKM (liver ... diseases #diagnosis #table ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Manifestations: Malar rash ... - Cytopenia: Common ... Positive in 60-80% of cases ... : Chronic disease ... #Summary #rheumatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 • NASH ... , Chronic viral ... injury: > 3 • Chronic ... transaminitis #LFTs
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... : Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Alcohol, Viral hepatitis ... (VIII is most common ... RA, SLE), Post-partum ... comparison #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
PLT in selected cases ... test, ANA (e.g., SLE ... gastric bypass), LFT ... (liver disease) ... Causes #Workup #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... disease • Liver ... diseases and hepatitis ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Noninfectious hepatitis ... Kidney disease common ... with Lupus: • Chronic ... Erythematosus #Diagnosis #Rheumatology