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hepatology diagnosis hbv algorithm differential hepbv druginduced hepatitis transaminitis aclf acute aih antivirals autoimmune chemistry cirrhosis comparison daas dili failure
Hepatitis B Phases and Treatment Phase 1 - HBeAg+ Chronic Infection Phase 2 - HBeAg+ Chronic Hepatitis Phase 3
Hepatitis B Phases ... + Chronic Hepatitis ... - Chronic Hepatitis ... #HBV #HepBV #Phases ... #Treatment #Management
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... between the above phases ... HAV immunity; Liver ... Chronic Hepatitis ... #Treatment #Hepatology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
antivirals (DAAs) for chronic ... DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology ... #Management #Pharmacology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 5-10x normal - Chronic ... normal - Hemolysis, NASH ... #Injury #hepatology ... #LFTs #transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... e.g. ascites), Chronic ... hepatitis fibrosis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Injury (DILI) ... Viral Hepatitis ... #Cirrhosis #Hepatology
Phases of chronic HBV infection according to revised and classical definitions Phase 1: HBeAg+ chronic infection (old
Phases of chronic ... HBV infection according ... #HBV #HepBV #Phases ... #Treatment #Management ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... disease: > 2 • NASH ... , Chronic viral ... : > 3 • Chronic ... transaminitis #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... disease: > 2 • NASH ... , Chronic viral ... : > 3 • Chronic ... #injury #hepatitis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2 ... mg/dL) or acute liver ... #Indications #management ... #hepatology
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