13 results
You’ll notice there is an IgM and an IgG core antibody. The presence of IgM anti-HBc
indicates an acute HBV ... when fighting a HBV ... indicates a chronic HBV ... infected with HBV ... commonly run in the clinical
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... lesion: Clinical ... Infections: - ... Viral: VZV, HSV, ... HIV, CMV, HTLV
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
of the spinal cord ... Transverse Myelitis - Clinical ... disordersInfections ... simplex virus, HIV ... diagnosis #management #neurology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... : HCV infection, ... HBV infection, ... HIV infection ... cytoplasmic antibody
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
cord - Spinal Cord ... result in permanent neurologic ... Infarction - Infection ... syphilis, and HIV ... differential #diagnosis #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
early stages of infection ... areas of high signal ... Clinical Presentation ... : The clinical ... dementia #AIDS #Neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... , autoimmune disorder ... Clinical Presentation ... Mycoplasma, EBV, HIV ... hemolytic #anemia #hematology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... Lesions of the spinal ... cord • Inflammatory ... • Inflammatory disorders ... parainfluenza, Coxsackie, HIV
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... • Avg age of DX ... to 8 years Clinical ... DDX - Other causes ... Epstein-Barr syndrome, HIV
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulinemia Associated Disorders ... Malignancy • Infections ... Cryofibrinogenemia DDX ... • TTP, HUS and HIT ... Cryofibrinogenemia #diagnosis #rheumatology