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diagnosis differential hematology management anemia spinal spinalcord syndromes vasculitis agglutinin aids algorithm antibody antigens aplastic associated bee classification cold common
You’ll notice there is an IgM and an IgG core antibody. The presence of IgM anti-HBc
indicates an acute HBV ... when fighting a HBV ... indicates a chronic HBV ... infected with HBV ... commonly run in the clinical
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV ... early stages of infection ... Clinical Presentation ... : The clinical ... dementia #AIDS #Neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... Viral: VZV, HSV, ... HIV, CMV, HTLV ... disorders #diagnosis #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... ruled out • Brain ... MRI: Check for brain ... simplex virus, HIV ... diagnosis #management #neurology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... : HCV infection, ... HBV infection, ... HIV infection ... classification #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Clinical Presentation ... Mycoplasma, EBV, HIV ... hemolytic #anemia #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... to 8 years Clinical ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
nervous system: Brain ... of the spinal cord ... : Brain abscess ... parainfluenza, Coxsackie, HIV ... Differential #Diagnosis #neurology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
meninges in spinal cord ... nerve roots Spinal Cord ... (IRIS): • In HIV ... contrast enhancement Brain ... and not direct infection
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Infarction - Infection ... syphilis, and HIV ... sclerosis • Clinical ... differential #diagnosis #neurology
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