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diagnosis differential anca antineutrophil antinuclear antinxp2dm autoimmune erythematosus hematology lupus management monoclonal myopathy myositis paraproteinemias sle table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... ANA - Non-specific ... (TTG) - Celiac disease ... diseases #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... dermatomyositis ... connective tissue disease ... 90% • Anti-GBM disease ... diseases
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Antibodies targeting ... had more severe disease ... #AntiNXP2 #Dermatomyositis ... #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... tissue disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... macular Vasculitis) Autoantibodies ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Interstitial lung disease ... Interstitial lung disease ... Interstitial lung disease ... skeletal muscle disease ... myocarditis Other Diseases
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