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classification management sle vasculitis associations comparison cryoglobulinemia cryoglobulins druginduced igg4 phenotypes related testing types vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... • Rheumatic Diseases ... #patterns #rheumatology ... #diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Diseases: • Homogeneous ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... their Disease Associations ... hepatitis Anti-CCP, Rheumatoid ... #diagnosis #table ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... fever) and laboratory ... vasculitis, rheumatoid ... rheumatologic diseases ... #Diagnosis #Rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... #diagnosis #rheumatology ... #table #ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... lupus erythematosus ... #Disease #Rheumatoid ... #workup #diagnosis ... #testing #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% ... lupus erythematosus ... (SLE), rheumatoid ... arthritis, Sjögren's ... classification #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... (antinuclear antibodies ... , rheumatoid factor ... IgG4 #Related #Disease ... #treatment #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
of autoantibodies ... Lupus Erythematosus ... Evolution: Chronic disease ... #rheumatology # ... diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis: Systemic ... rheumatic diseases ... lupus erythematosus ... ) pattern: antibodies ... #diagnosis #rheumatology
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