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lupus erythematosus sle ana antibodies differential druginduced hematology management monoclonal paraproteinemias
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... c-ANCA - Vasculitis ... (TTG) - Celiac disease ... diseases #diagnosis ... #table #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... with auto-immune diseases ... #autoantibodies ... #rheumatology # ... table #ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Still disease, ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... ) Autoantibodies ... anemia due to cold IgG ... Sneddon-Wilkinson disease ... #Oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... 95% (IgG anti-chromatin ... Evolution: Chronic disease ... #table #rheumatology ... #diagnosis #management
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