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differential ana antinuclear erythematosus management associations classification comparison druginduced myopathy myositis patterns rheumatic rheumatoid tafro testing thrombocytopenia vasculitides vasculitis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... #diagnosis #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Syndrome (SS), ... (SLE), Systemic ... : Lupus (SLE), Systemic ... , Sjögren Syndrome ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rheumatologic diseases ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, Arthritis, myalgia ... months to years) Systemic ... Evolution: Chronic disease ... #table #rheumatology ... #diagnosis #management
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
and Systemic lupus ... Association with disease ... overlap syndromes ... with auto-immune diseases ... table #ANA
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... diseases, such ... as systemic lupus
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... connective-tissue disease ... #Rheumatic #Disease ... #laboratory #workup
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Interstitial lung disease ... Antisynthetase syndrome ... lymphoma Overlap Syndrome ... ANTI-SYNTHETASE SYNDROME ... paraneoplastic syndrome
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
multicentric Castleman disease ... (SLE), Sjögren’ ... s syndrome, ANCA-associated ... infection, rickettsial disease ... , Lyme disease,
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