Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic lupus symptoms management anca table associations myositis antinuclear differential

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Autoantibodies in Rheumatology
• Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and

Lupus (SLE): ANA ... Peptide (CCP) • Myositis ... • Scleroderma (Systemic ... diagnosis #associations ... #table

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

context of other symptoms ... : Lupus (SLE), Systemic ... , Myositis, Mixed ... #patterns #rheumatology ... #diagnosis #differential

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

and Systemic lupus ... SLE-SSc-AlM overlap syndromes ... #autoantibodies ... #Systemic #lupus ... #table #ANA

Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
• Epidemiology: -10% of all lupus cases, drug-dependent,

months) and of autoantibodies ... months to years) Systemic ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... : • Symptoms limited

Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain

- Differential ... (also seen in association ... Mechanic's hands Autoantibodies ... • Conduction system ... #differential #

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