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classification primary algorithm anca antibodies antibody antinuclear aortitis autoimmune cryoglobulinemia cryoglobulins endocarditis erythematosus functional hematology htn hypertension infectiousdiseases lupus mitral
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
• Sjögren syndrome ... connective tissue disease ... 90% • Anti-GBM disease ... #rheumatology # ... diseases
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... polychondritis, Behcet's Disease ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(Granulomatous disease ... Diagnosis: Systemic ... rheumatic diseases ... atherosclerotic disease ... differential #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... classification #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... ) Autoantibodies ... Sneddon-Wilkinson disease ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... diseases, such ... atherosclerotic disease ... #Differential #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Diagnosis: • ANCA-associated ... tissue disease ... diseases (i.e. ... ) • Kikuchi disease
Causes of Primary and Functional Mitral Regurgitation (MR) Causes of primary mitral regurgitation - Rheumatic heart
Rheumatic heart disease ... , Barlow's disease ... disease: Collagen ... vascular disease ... #Diagnosis #Cardiology
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm Primary (Essential) (95%) - Onset between age
taken at home, work ... Renal parenchymal disease ... • Renovascular disease ... excess (Cushing syndrome ... or disease)
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Differential Diagnosis ... Pre-existing valvular disease ... Congenital heart disease ... • Metastatic disease ... #Diagnosis #cardiology
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