20 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... , Drug-induced Lupus ... , Drug-Induced Lupus ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Workup: - ANA ... life-threatening • Treatment ... management of SLE • Evolution ... : Chronic disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Workup: - ANA ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... : Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... lymphoproliferative syndrome Clinical ... vein thrombosis Hematologic ... antibodies • (-) ANA
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... lupus anticoagulant ... Willebrand syndrome • Lupus ... administration, evaluation ... #Diagnosis #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... Fever is the main clinical ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... : Discoid lupus ... comorbid disease ... • Laboratory evaluation ... DHEAS) • ANA
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... Unknown cause Treatment ... inhibitors under evaluation
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
indicate the initial evaluation ... history alongside evaluation ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... Liver #Enzymes #Differential