8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... : fever +++, hepatosplenomegaly ... management #treatment #summary ... #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... cells can indicate disease ... workup #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... following: • Fever ... Low or absent NK cell ... management #treatment #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
clinical associations ... symptoms - Headache, fever ... doi: 10.1111/all ... Urticaria #diagnosis #rheumatology ... #comparison #table
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Management Summary ... Clinical Exam: ... active ROM +/- fever ... necrosis, Lyme disease ... 90% sensitive in pediatrics
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
) - Summary Overview ... immunophenotype Clinical ... ) B symptoms → fevers ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Management Summary ... include low-grade fevers ... CLINICAL: • Physical ... with significant fevers ... diagnosed based on clinical
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... ▪ Autoimmune diseases ... Clinical Presentation ... #HLH #Hemophagocytic ... Diagnosis #Management #Hematology