23 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... #APML #diagnosis ... #management #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... #treatment #hematology ... #oncology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... #Differential #Causes ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management ... #Workup
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
or iatrogenic causes ... Plan definitive management ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
APL valve (Box ... o Aspiration, pulmonary ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
APL valve <3 breaths ... o Endocrine cause ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
overload / TURP syndrome ... ) • Medical causes ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
APL valve. ❺ Circulation ... CardiacArrest #Checklist ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup