15 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... activity • ↓ LAP ... - infiltrates (anemia ... (CLL) and/or Small ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
large numbers and ... and other C Cell ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Lymphoblastic Leukemia ... Cytarabine #ALL ... Treatment #timeline #oncology ... #pediatrics #peds ... #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
MD) - Diagnosis and ... cytopenias (usually anemia ... transformation to acute leukemia ... #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
5) Symptoms of anemia ... lymphadenopathy and ... marrow failure with anemia ... #oncology #hematology ... hemeonc #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Workup History ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... not required in all ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Workup: • Complete ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... et diutinum Neurologic ... (-) hemolytic anemia ... Pseudohyponatremia • ↓anion gap ... Differential #Diagnosis #Oncology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Management Summary ... pernicious anemia ... with tendency to fall ... antibody that works ... #treatment #neurology