15 results
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Ocular Myasthenia ... anti-ACh antibodies ... always ask your ... PhysicalExam #clinical #video ... ophthalmology #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... (AG) = {Na - (Cl ... bowel syndrome, ... Classically” noted with pulmonary ... ABG #bloodgas #Acid
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
Acidosis (HAGMA) - Differential ... Glycols - ethylene and ... associated with short ... bowel syndrome ... underexcretion of acids
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... poisoning Normal acid-base ... potassium acid ... #differential #
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Hypergammaglobulinemic macular ... Evans • ITP • Cl-NH ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Imaging: CXR- pulmonary ... initiation • Differential ... management #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
vancomycin (if SSTI or port ... Phos, high uric acid ... rasburicase if uric acid ... (~20 %) and APL ... renal failure, pulmonary
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
mobilizes fatty acids ... produce Acetoacetic acid ... In both SK and AK ... for Refeeding Syndrome ... #diagnosis #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... affects the skin, neurologic ... cognitive impairment, neurologic ... disease, and ocular
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... vitamin B12 or folic acid ... Antibiotics such as ... blood count with differential ... diagnosis #hematology #oncology