29 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
• Mechanism: Exchanges ... calcium for K; also binds ... nonspecifically binds ... #pharmacology #table ... #comparison #binders
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... Kayexelate #Comparison #Table ... Pharmacology #Patiromer #HyperKalemia
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... higher risk of hyperkalemia ... potential Ca2+ channel ... failure Ca2+ channel ... contraindications #table
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... since they are not able ... aluminum-based phosphate binder ... calcium-based phosphate binders ... restricted due to hypercalcemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... • Consider K+ binder ... potassium and ECG changes ... , asystole #hyperkalemia
Ventricular Tachycardia - Management Algorithm
Wide Complex Tachycardia: Rate > 100, QRS > 120
DDx: Ventricular tachycardia, SVT
Tachycardia - Management Algorithm ... aberrancy, SVT iso Na channel ... blocker, Hyperkalemia ... VTach #Management #Algorithm
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... #Phosphate #Binders ... #Table #Comparison
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; changes ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... cyclosilicate #Potassium #Binders ... #Management #Hyperkalemia ... #pharmacology #table
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
and Management Algorithm ... digoxin, calcium channel ... beta-blockers, calcium channel ... Electrolytes (hyperkalemia ... #Bradycardia #Algorithm