8 results
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm
Central Nervous System - Decreased LOC, Axial
Causes of Hypotonic ... Infant (Floppy ... Nervous System - Decreased ... Strength, Normal Reflexes ... #Causes #Peds #
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... an involuntary reflex ... #Meningitis #Clinical ... PhysicalExam #Pediatrics #Peds
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... deficiencies present in infants ... Signs/Symptoms/Complications ... endocrinology #peds
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... pain, numbness, decreased ... reflexes Pathophysiology
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Infants ≤6 months ... if they have no clinical ... lack of tapering, decreased ... and lab signs ( ... #Diagnosis #Peds
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... - Causes progressive ... Increased Jaw Jerk reflex ... - Fatigue and decreased
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... Cauda equina- decreased ... Non-compressive Spinal Cord Causes ... differential #algorithm
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Spasticity - Reflexes ... : decreased or absent ... • Bilateral signs