31 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
calcium for K; also binds ... Initial: 8.4 g QD; increase ... nonspecifically binds ... #pharmacology #table ... #comparison #binders
Causes of Hypokalemia - Differential Diagnosis Algorithm
Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... - Differential ... Decreased filling ... #Differential # ... #workup #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... - Differential ... of injection Decreased ... #Differential # ... Diagnosis #Causes
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... iron that may decrease ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #Nephrology
Causes of Hypokalemia

Hypokalemia results from abnormal losses, transcellular shifts, or insufficient intake (Table 1).6–8 Abnormal losses
Causes of Hypokalemia ... insufficient intake (Table ... in response to decreased ... #Differential # ... Causes
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Decreased Mg ... #Differential # ... Algorithm #Diagnosis #Causes ... #Workup #Nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Hyporeflexia: • Hypercalcemia ... #differential # ... diagnosis #table ... #neurology
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Hypophosphatemia - Differential ... Algorithm • Decreased ... Malabsorption, Phosphate binder ... Diagnosis #Algorithm #causes ... #nephrology #phosphate
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
by Mechanism Decreased ... - Hypokalemia ... Hypomagnesemia #Differential ... Low #Magnesium #Table ... Classification #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... vasoconstriction → decreased ... fluid/Lactated ringers ... per day until stable