23 results
Tweetorial - Stevens Johnson Syndrome (SJS)

By Dr. Steven Chen @DrStevenTChen

#StevensJohnsonSyndrome #SJS #Dermatology #Diagnosis #Tweetorial #Pathphysiology
Stevens Johnson Syndrome ... (SJS) By Dr. ... StevensJohnsonSyndrome #SJS ... #Dermatology #Diagnosis ... #Tweetorial #Pathphysiology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... SJS/TEN DRESS ... involvement: 50% have ... SCVMCMed #DRESS #Syndrome ... #table #dermatology
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
macule and papule (Table ... Those with centrally ... rashes but without signs ... pathognomonic for SJS ... #Diagnosis #Dermatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... differentiating between the diagnosis ... #TEN #Dermatology ... Video #Clinical #SJS
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Yellow Nail Syndrome ... Nail Pitting • Central ... #differential #diagnosis ... #dermatology #nails ... #table #lines
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Yellow Nail Syndrome ... Nail Pitting • Central ... #differential #diagnosis ... #dermatology #nails ... #table #lines
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
the Nikolsky sign ... staphylococcal scalded skin syndrome ... (SSS) in infants ... and toxic shock syndrome ... #Diagnosis #Dermatology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... disc herniation (central ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... capillary leak syndrome ... • Schnitzler syndrome ... light chain vs. heavy ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology