10 results
diagnosis differential monoclonal chronic cll gammopathy lymphocytic management significance anemia aplastic clinical defects gap globulin hemeonc inherited mds myelodysplasia myelodysplastic
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... capillary leak syndrome ... light chain vs. heavy ... Differential #Diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... disorder characterized ... immunoglobulin heavy-chain ... #Significance #hematology ... #diagnosis #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • MGCS • MGRS ... • CLL & MBL • Heavy ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... in adults • Disorder ... →several RCTs have ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... , breast CA - Hematologic ... - Lupus - Leukemia ... #diagnosis #dermatology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... • Exposure to heavy ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... than 50 years who have ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... MYH9-Related Disorder ... non-muscle myosin heavy ... Platelet #Defects #comparison ... differential #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Gammopathy Include: • MGUS ... changes (POEMS syndrome ... gastric tumors • Hematology ... differential #diagnosis #hematology
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