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diagnosis rheumatology sle classification management patterns symptoms vasculitis activation autoantibodies disease eularacr gca giantcell laboratory macrophage mas mimickers monoclonal paraproteinemias
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... Juvenile Idiopathic Arthritis ... lupus erythematosus ... lupus erythematosus ... #Antibodies #ANA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
for Systemic Lupus ... Clinical Domains ... • Arthritis domain ... least 2 joints • Neurologic ... #Lupus #Erythematosus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... : - ANA 95-100% ... Diagnosis and Lupus ... #Lupus #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , inflammatory arthritis ... vasculitis, rheumatoid arthritis ... Arthritis: • ... Symptoms limited to: Arthritis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... lupus erythematosus ... juvenile idiopathic arthritis ... lupus erythematosus ... Diagnosis #Management #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... lupus erythematosus ... purpura: strong sign
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... et diutinum Neurologic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Diseases • Septic arthritis ... lupus erythematosus ... of Inflammatory Arthritis ... when rheumatoid arthritis ... Disease #Rheumatoid #Arthritis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... arteritis (GCA) ... , neurologic, and ... versus Temporal Arteritis ... #GiantCell #arteritis
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