19 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... predispose to other orthopedic ... #Disease #differential ... #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... parvovirus, HIV, hepatitis ... #rheumatology # ... approach #workup #differential
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
- Differential ... Diagnosis Algorithm ... Intra-Articular - Bone ... Osgood-Schlatter Disease ... #Orthopedics #Causes
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain ... - Differential ... Diagnosis Algorithm ... Peripheral Vascular Disease ... #Orthopedics #Causes
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... the subchondral bone ... #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... Fever/Chills/Joint ... Parvovirus - Hepatitis ... - Aneurysmal bone
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework ... Bone/Joint Causes ... Psoriasis • Hepatitis ... • Hematoma
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... hemolysis, bleeding, hematoma ... hemolysis) • ALP: Bone ... #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hepatic infarcts, Hematomas ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Jaundice - Hepatitis ... Heberden's nodes (DIP joints ... #pain #differential ... #diagnosis #rheumatology