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diagnosis rheumatology differential erythematosus sle symptoms systemic approach autoantibodies classification emergency gap globulin headache joint laboratory mimickers msk pain protein
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... - Hemolytic anemia ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... spondyloarthropathies, lupus ... Inflammatory, crystalline disease ... #approach #workup ... #differential #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... joint • Systemic lupus ... the presence of anemia ... #laboratory #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... such as systemic lupus ... purpura: strong sign ... #diagnosis #rheumatology
Emergent Causes of Headache and Associated Risk Factors Carbon monoxide poisoning - Breathing in enclosed or confined
immunization Temporal arteritis ... collagen vascular diseases ... (eg, systemic lupus ... headache #redflags #signs ... #symptoms #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... (RA, Temporal arteritis ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
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