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diagnosis rheumatology differential management dermatology joint oncology pain sle syndrome adultonset approach behcet classification comparison druginduced erythematosus gap globulin mds
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection • Lyme disease ... migrans • Lyme disease ... • Gonococcal arthritis ... lesions • Discoid lupus ... #rashes #differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... , Skin rash ± odynophagia ... fraction < 20% Differential ... diagnosis #management #treatment ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... vein thrombosis Hematologic
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... test (this is a skin ... ) Differential Diagnosis ... , AS Treatment: ... signs #symptoms #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... of the joints (arthritis ... , breast CA - Hematologic ... ’s syndrome - Lupus ... Treatment: - Systemic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... Differential ... such as systemic lupus ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... spondyloarthropathies, lupus ... Inflammatory, crystalline disease ... #approach #workup ... #differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... Myeloproliferative Disease ... blood count with differential ... Syndromes #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... (RA, Temporal arteritis ... Gap #ProteinGap #differential ... #diagnosis #hematology
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