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aflp causes liver obstetrics pregnancy coagulation comparison disease disseminated fatty hellp hepatitis icp intravascular obgyn pathophysiology treatment
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Erythropoiesis • Hematoma ... Diagnosis #Algorithm ... #Causes #Hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... Hepatic infarcts, Hematomas ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... #diagnosis #icp
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
rapidly develops (DIC ... , ascites, jaundice ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Liver #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Acral cyanosis • Hemorrhagic ... Subcutaneous dissecting hematoma ... #Coagulation #diagnosis ... #hematology
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