9 results
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Hepatic infarcts, Hematomas ... extensive necrosis and hemorrhage ... DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Erythropoiesis • Hematoma ... Dilatation on Ultrasound ... #Causes #Hepatology
Causes of Altered Level of Consciousness GCS < 7 - Differential Diagnosis Algorithm

Brain Involvement - Hemispheric
Diagnosis Algorithm ... Hemispheric • Hemorrhage ... fracture • Subdural hematoma ... Vasculitis • TTP • DIC ... - Excesses • Liver
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
of Post-Partum Hemorrhage ... - Differential ... Diagnosis Algorithm ... Vaginal laceration / hematoma ... intravascular coagulation (DIC
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... red to purple, hemorrhagic ... Thrombocytopenia: ITP ... deficiency • Liver ... #Diagnosis #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
rapidly develops (DIC ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Acral cyanosis • Hemorrhagic ... Subcutaneous dissecting hematoma ... • Severe Liver ... causes #treatment #management ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... than 2 mm) of hemorrhage ... fulminans - DIC ... • Abdominal ultrasound
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... hemolysis, bleeding, hematoma ... #diagnosis #algorithm ... #hepatology