6 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
(DIC) Overview ... Bleeding (64%) • Renal ... Subcutaneous dissecting hematoma ... #diagnosis #causes ... treatment #management #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Hepatic infarcts, Hematomas ... DIC • Aminotransferases ... Microvesicular fat ... #hepatology #obstetrics ... #differential #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... rapidly develops (DIC ... Antithrombin Ill • Ultrasound ... #hepatology #obstetrics ... #obgyn #diagnosis
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
metabolism and coagulation-mediated ... children, so I did ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
to liver than AST ... • Albumin • Coagulation ... hemolysis, bleeding, hematoma ... liver #chemistry #diagnosis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... melanoma, myeloma • Pregnancy ... hemolysis, bleeding, hematoma ... #differential #diagnosis ... #algorithm #hepatology