9 results
Common toxicities of antifungal agents. 
CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
toxicities of antifungal ... CNS = central nervous ... #antifungal #toxicities ... SideEffects #Adverse #Pharmacology ... #InfectiousDiseases
Antifungal Coverage Activity Antibiogram 

Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... Echinocandins #Pharmacology ... #InfectiousDiseases
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... Itraconazole has poor CNS ... Isavuconazole(PO or IV) #Pharmacology ... Overview #Azoles #Antifungal
Antibiogram - Antibiotic Resistance Table for Severe Multidrug Resistant Bacteria

ESBL Enterobacteriaceae
Carbapenem-Resistant Enterobacteriaceae
MDR Pseudomonas Aeruginosa
Carbapenem-Resistant Acinetobacter

Adapted from
Antibiotic #Resistance #InfectiousDiseases ... #Resistant #Comparison ... #Table #Pharmacology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
nervous system (CNS ... effects on the CNS ... effects on the CNS ... #medications #pharmacology ... #comparison #table
Balamuthia vs Acanthamoeba vs Naegleria - Comparison
Exposure - Host - CNS disease - CNS spread -
vs Naegleria - Comparison ... Exposure - Host - CNS ... disease - CNS spread ... Acanthamoeba #Naegleria #Comparison ... #Table #InfectiousDiseases
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
with additional CNS ... margin of safety in pharmacology ... Pharmacokinetics #Comparison ... #Table #Pharmacology
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
Overview of antifungal ... management #treatment #antifungals ... #comparison #table ... #pharmacology
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
treat susceptible CNS ... in treatment of CNS ... #Penetration #CNS ... Antimicrobials #InfectiousDiseases ... #Pharmacology