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Oxygen Hemoglobin Dissociation curve

Curva de disociacion de oxi-hemoglobina
 #Cardiology#CEM
Oxygen Hemoglobin ... disociacion de oxi-hemoglobina
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Oxygen-Hemoglobin ... MatthewHoMD #Oxygen ... #Hemoglobin #Dissociation
Oxygen Delivery Equation
DO2 = CO x {(1.39 x Hb x sO2) + (PaO2 x 0.03)}
DO2 =
Oxygen Delivery ... Concentration of Hemoglobin ... capacity of hemoglobin ... saturation of effective hemoglobin ... Number of baskets = Hemoglobin
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
- insufficient oxygen ... Hypoxemia - low oxygen ... - atmospheric oxygen ... saturation of hemoglobin ... loss) or abnormal hemoglobin
GHOST CAP - Neuro ICU Checklist Mnemonic
G - Glycemia
H - Hemoglobin
O - Oxygen
S - Sodium
T -
Glycemia H - Hemoglobin ... O - Oxygen S
Pulse Oximetry Summary
Pulse oximetry is the non-invasive continuous measurement of the oxygen saturation of hemoglobin. It
measurement of the oxygen ... saturation of hemoglobin ... that oxy- & deoxy hemoglobin
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
DPG so that the oxygen ... which shifts the oxygen ... left and makes oxygen ... a shift in the hemoglobin
DO2 Equation in Shock = Oxygen Delivery
DO2 = CO x (1.39 x [Hb] x SaO2 +(0.003xPaO2))
DO2
Equation in Shock = Oxygen ... DO2 = Rate of oxygen ... binding capacity of haemoglobin ... per gram [Hb] = Haemoglobin ... litre) SaO2 = Haemoglobin
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
breathing; provide oxygen ... PRBC infusion for hemoglobin
Thalassemias on Hemoglobin Electrophoresis
Beta-Thalassemia:
 • Major
 • Intermediate
 • Trait
Alpha Thalassemia:
 • Trait-1 (α α/ α-)
Thalassemias on Hemoglobin ... or (α α/ --) • Hemoglobin ... H (α -/ --) • Hemoglobin ... Barts(- -/ --) Hemoglobin ... #Thalassemias #Hemoglobin