35 results
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... autoimmune (most of the causes ... reactions) - Dr ... #Classification
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
reactions Type ... Hours to Days (Hemolytic ... Anemia) Type ... hypersensitivity #reactions ... #Types #Classification
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Other: Transfusion reaction ... - Transfusion reaction ... Extravascular #Causes ... differential #diagnosis #hematology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
thrombocytopenia, Autoimmune Hemolytic ... Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... reactions. ... Allergen-specific lgE causes ... , Haemolytic disease ... #table #classification
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... • Transfusion reactions ... udaygulati #Hemolytic ... #classification ... #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Differential Diagnosis Table ... Disease Mixed-type ... #Autoimmune #Hemolytic ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... Coombs • IgG type ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... or during hemolytic ... #Classification ... Allergy #Diagnosis #Reactions ... #Table
Summary of types of haemolytic anaemia. Visit gramproject.com for more medical diagrams, tables and flowcharts for
Summary of types ... of haemolytic anaemia ... medical diagrams, tables ... algorithm #anaemia #haematology