29 results
diagnosis differential pathophysiology rheumatology management arteritis pulmonary temporal disease gca giantcell giantcellarteritis infections neurology nutrition ra syndrome treatment acquired acute
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... - Normocytic Anemia ... palpation - Vasculitic ... #Symptoms #Vasculitis
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries Takayasu's arteritis: - Onset < 40 yrs -
- Asymmetric pulse ... yrs - Cranial symptoms ... multiplex ANCA vasculitis ... pulmonary nodules - Hemoptysis ... Leukocytoclastic vasculitis
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Pulmonary: Cough, hemoptysis ... dysrhythmias • Ophthalmologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... Endocarditis, Aortic ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... branches • GCA: - Aorta ... Presentation - Systemic Symptoms ... purpura: strong sign ... diminished, or tender pulses
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... diminished, or tender pulses ... < 30 years • Aorta ... claudication, pulse ... Arteritis): • Aorta
Low O2 saturation that does not respond to supplemental O2 - Key diagnostic feature (sat < 85%
averaging by the pulse ... FiO2 Severity of symptoms ... pneumonia, COPD, anemia ... Concentrations #Signs ... #Symptoms
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... of anemia include ... • hemolytic anemia ... • Compensated hemolysis ... intravascular hemolysis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
bloodstream Hemolysis ... • Hemolytic Anemias ... - Pernicious anemia ... tumor burden) Vasculitis ... associated with any symptoms
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
2) Typical symptoms ... • Cephalic symptoms ... Constitutional symptoms ... Doppler US : halo sign ... #Rheumatology #Ophthalmology
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